Yoshida would be captain in Hojbjerg's absence, I imagine.
I would play Romeu and Danso in front of a back four. There is a proper player in Armstrong, but he needs to be further up the pitch, as he tends to make horrific mistakes when near his own goal. I would put him in the centre of an attacking midfield 3, flanked by Djenepo (when fit) and Boufal. Redmond is flattering to deceive again at the moment. Ward-Prowse and (much as I hate to write this) Hojbjerg need to go back to school. Primary, if necessary.